Ibuprofen (Advil, Motrin, Nurofen) is much more toxic to dogs than to people. The risk depends on the total milligrams and your dog's weight.
| Dose | Possible effect |
|---|---|
| 100–125 mg/kg | Vomiting, diarrhea, belly pain |
| 175–300 mg/kg | Kidney failure |
| Over 400 mg/kg | Seizures, wobbliness, coma |
| Over 600 mg/kg | Potentially lethal |
Example: one 200 mg tablet is 20 mg/kg for a 10 kg (22 lb) dog, but 80 mg/kg for a 2.5 kg (5.5 lb) dog. Repeated smaller doses can also cause stomach ulcers.
Stomach signs can take a day or more to appear, and kidney damage can be silent at first.
US & Canada, a fee may apply. Outside North America, call your nearest emergency vet.